According to the latest report published by Credence Research, Inc. “Global Saline Laxatives (Magnesium Citrate, Magnesium Hydroxide, Sodium Phosphates; Prescribed and OTC Drugs) Market – Growth, Future Prospects and Competitive Assessment, 2016 – 2022,” the saline laxatives market was valued at USD 303.6 Mn in 2015, and is expected to reach USD 490.5 Mn by 2022, expanding at a CAGR of 8.3% from 2016 to 2022.
Saline laxatives are osmotic laxatives that work by drawing fluids into the bowel from surrounding tissue, thus softening stools and assist in easy fecal discharge. Saline laxatives are largely used for swift emptying of bowels to prepare for examination or surgery, eliminating drugs and food during poisoning or overdose and obtaining fresh stool sample for testing. These drugs are distinct from conventional bulk forming laxatives and hence are not usually used for treating constipation.
The global saline laxatives market is anticipated to witness a steady progress during the forecast period due to high demand for and wide availability of these products over-the-counter. Non-prescribed use of saline laxatives for immediate weight loss is also common. The demand for saline laxatives is widely witnessed in senescent population, where immediate and regular voiding of bowel is a prime usage factor. Hence, abuse of saline laxatives is predominantly found in this age group, particularly in the developed markets where awareness about the range of available laxatives is high.
Magnesium Citrate, Magnesium Hydroxide and Sodium Phosphates are the major saline laxatives. Brands such as Phillips’ Milk of Magnesia, OsmoPrep, Fleet Enema, Phillips’ M-O, Ceo-Two are some of the major names in the global market. Since magnesium and phosphate are the key ingredients in saline laxatives, their use is discouraged to use in patients with renal failure. Reported adverse effects such as nephrocalcinosis, acute phosphate nephropathy, and renal failure associated with excessive use of oral sodium phosphates has urged the USFDA to issue warning with respect to unsolicited use of such drugs.
The overall saline laxatives market is moderately competitive, and is characterized with existence of some key brands that monopolize the market. Some of the major players in this space are Beutlich Pharmaceuticals, LLC, C.B. Fleet Company, Inc., Salix Pharmaceuticals, Bayer AG and others.
The global saline laxatives market is studied for the following drug types:
1. Magnesium Citrate
2. Magnesium Hydroxide
3. Sodium Phosphates
Saline laxatives are milder forms of mainstream laxatives and are mostly used for rapid emptying of bowel. These drugs are often used for preparation before surgery, for elimination of foods and drugs after poisoning or to obtain fresh stool sample. Saline laxatives work by absorbing fluid into the bowel thus softening the stools, enabling their rapid discharge. Saline laxatives contain magnesium, citrate, sulphate and phosphate ions as active ingredients. Milk of Magnesia and Fleet phosphor-soda are the most renowned saline laxatives commercially available. The demand for OTC saline laxatives is the highest. However, their excessive and un-scrutinized use is discouraged on the grounds of reported renal failure, nephrocalcinosis and acute phosphate nepthropathy.
Geographically, the saline laxatives market is cumulative to North America, Europe, Asia-Pacific, Middle East and Africa and Latin America.
North America dominates the saline laxatives market both in terms of consumption and revenue generation followed by Europe. High use of medication for mild constipation, greater awareness and wide availability of a range of products are the key factors contributing to the dominance of these regions. Latin America is anticipated to follow the trends prevalent in North America market. Asia-Pacific is anticipated to be the fastest growing market among all the regions. Gradual growth in awareness in the patient population, growing availability of cost-effective drugs are the key factors driving the Asia-Pacific markets. Growing prevalence of constipation in this region and large pool of target geriatric population are among the other drivers contributing to the growth of Asia-Pacific saline laxatives market.
Based on prescription type the global saline laxatives market is studied for the following types:
1. Prescribed Saline laxatives
2. Over-the-Counter Saline Laxatives
Saline laxatives form a very small section of the overall laxative drugs available in the market. High prevalence of constipation and corresponding lack of reporting until acute stages contribute to high levels of self-prescription of laxatives. Osmotic laxatives have been available for decades in the market, and patent protection of these products has long expired. These factors significantly contribute to the larger market share of over-the-counter sales of saline laxatives. However, the reported risk of acute phosphate nephropathy in patients has led to a controlled restrain on excessive OTC demand for saline laxatives. The demand for mild saline laxatives such as oral magnesium hydroxide is observed to be higher through OTC sales…
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